Evaluation of cerebral blood flow in the hippocampus, thalamus, and basal ganglia and the volume of the hippocampus in dogs before and during treatment with prednisolone

CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that GC administration reduced CBF in the hippocampus and thalamus in dogs of the present study, similar to that which occurs in humans. Research on GC-related brain alteration in dogs could potentially contribute to advancements in understanding Alzheimer disease in humans and neurodegenerative conditions in dogs.PMID:33629902 | DOI:10.2460/ajvr.82.3.230

Source: American Journal of Veterinary Research - February 25, 2021 Category: Veterinary Research Authors: Kentaro Yamazaki Aritada Yoshimura Shunsuke Miyahara Shoma Sugi Maho Itono Mina Kondo Nanako Tsuji Miki Shimizu Ryuji Fukushima Miori Kishimoto Source Type: research