Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis

by Kathryn E. Lafond, Rachael M. Porter, Melissa J. Whaley, Zhou Suizan, Zhang Ran, Mohammad Abdul Aleem, Binay Thapa, Borann Sar, Viviana Sotomayor Proschle, Zhibin Peng, Luzhao Feng, Daouda Coulibaly, Edith Nkwembe, Alfredo Olmedo, William Ampofo, Siddhartha Saha, Mandeep Chadha, Amalya Mangiri, Vivi Setiawaty, Sami Sheikh Ali, Sandra S. Chaves, Dinagul Otorbaeva, Onechanh Keosavanh, Majd Saleh, Antonia Ho, Burmaa Alexander, Hicham Oumzil, Kedar Prasad Baral, Q. Sue Huang, Adedeji A. Adebayo, Idris Al-Abaidani, Marta von Horoch, Cheryl Cohen, Stefano Tempia, Vida Mmbaga, Malinee Chittaganpitch, Mariana Casal, Duc Anh Dang, Paula Couto, Harish Nair, Joseph S. Bresee, Sonja J. Olsen, Eduardo Azziz-Baumgartner, J. Pekka Nuorti, Marc-Alain Widdowson, Global Respiratory Hospitalizations –Influenza Proportion Positive (GRIPP) Working Group BackgroundInfluenza illness burden is substantial, particularly among young children, older adults, and those with underlying conditions. Initiatives are underway to develop better global estimates for influenza-associated hospitalizations and deaths. Knowledge gaps remain regarding the role of influenza viruses in severe respiratory disease and hospitalizations among adults, particularly in lower-income settings. Methods and findingsWe aggregated published data from a systematic review and unpublished data from surveillance platforms to generate global meta-analytic estimates for the proportion of acute respiratory hospitalizations associate...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research