CNTN-1 promotes docetaxel resistance and epithelial-to-mesenchymal transition via the PI3K/Akt signaling pathway in prostate cancer.
Conclusions: The results of the present study suggest that downregulation of CNTN-1 may be an important mechanism to reverse chemoresistance in Dox-resistant PCa progression, thus shedding light on the development of novel anti-tumor therapeutics for the treatment of PCa.
PMID: 33488868 [PubMed]
Source: Archives of Medical Science - Category: Biomedical Science Tags: Arch Med Sci Source Type: research
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