Effects of diclofenac on sentinel species and aquatic communities in semi-natural conditions.

Effects of diclofenac on sentinel species and aquatic communities in semi-natural conditions. Ecotoxicol Environ Saf. 2021 Jan 17;211:111812 Authors: Joachim S, Beaudouin R, Daniele G, Geffard A, Bado-Nilles A, Tebby C, Palluel O, Dedourge-Geffard O, Fieu M, Bonnard M, Palos-Ladeiro M, Turiès C, Vulliet E, David V, Baudoin P, James A, Andres S, Porcher JM Abstract Due to the potential hazard of diclofenac on aquatic organisms and the lack of higher-tier ecotoxicological studies, a long-term freshwater mesocosm experiment was set up to study the effects of this substance on primary producers and consumers at environmentally realistic nominal concentrations 0.1, 1 and 10 µg/L (average effective concentrations 0.041, 0.44 and 3.82 µg/L). During the six-month exposure period, the biovolume of two macrophyte species (Nasturtium officinale and Callitriche platycarpa) significantly decreased at the highest treatment level. Subsequently, a decrease in dissolved oxygen levels was observed. High mortality rates, effects on immunity, and high genotoxicity were found for encaged zebra mussels (Dreissena polymorpha) in all treatments. In the highest treatment level, one month after the beginning of the exposure, mortality of adult fish (Gasterosteus aculeatus) caused effects on the final population structure. Total abundance of fish and the percentage of juveniles decreased whereas the percentage of adults increased. This led to an overall s...
Source: Ecotoxicology and Environmental Safety - Category: Environmental Health Authors: Tags: Ecotoxicol Environ Saf Source Type: research