Congenital diaphragmatic hernia —does the presence of a hernia sac improve outcome? A systematic review of published studies

Conclusion: This study shows significant survival benefits in newborns associated with presence of a CDH sac. This may be likely related to these infants having more favourable physiology with less severe pulmonary hypertension and/or smaller anatomical defects requiring primary closure only.What is Known:• Early reports have suggested survival benefits associated with a hernia sac in CDH.• Previous studies have included only a small number of patients.What is New:• A systematic review of published studies clearly shows that CDH newborns with a hernia sac have better overall survival outcomes and less severe pulmonary hypertension.• ECMO utilization and patch repair were also less often required in newborns with a hernia sac.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research