The relevance of miRNAs as promising biomarkers in lip cancer

ConclusionsThe upregulation of miR-181b, miR-31, and miR-345 expression in actinic cheilitis without epithelial dysplasia and the decrease in the expression of these miRNAs in actinic cheilitis with epithelial dysplasia and in lower lip cancer are potential biomarkers of malignant progression.Clinical relevanceThis miRNA signature can help to identify actinic cheilitis with potential to progress to lip cancer.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research