Pharmacokinetics of metformin in collagen-induced arthritis rats.

In conclusion, our study suggested that the reduced bioavailability of metformin in CIA rats is possibly related to the up-regulated function of the renal protein OCT2. PMID: 33434538 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33434538?dopt=Abstract

Source: Biochemical Pharmacology - January 9, 2021 Category: Drugs & Pharmacology Authors: Chen M, You G, Xie C, Yang R, Hu W, Zheng Z, Liu S, Ye L Tags: Biochem Pharmacol Source Type: research