Letter to the Editor: Obesity, diabetes, non-alcoholic fatty liver disease and metabolic dysfunction associated fatty liver disease are proinflammatory hypercoagulable states associated with severe disease and thrombosis in Covid-19

Obesity [1,2], diabetes [3,4], non-alcoholic fatty liver disease (NAFLD) [5] and metabolic dysfunction associated fatty liver disease (MAFLD) [6,7] are associated with severe Disease in Covid-19. High incidence (25 –70%) of deep vein thrombosis (DVT) had been reported in patients with severe COVID-19, particularly among those admitted to the intensive care units [8–10]. Obesity (BMI ≥30), Padua score > 4 and D-dimer>1.0 ( μg/ml) were associated with DVT in COVID-19 patients in multivariant analysis [9,10].

Source: Metabolism - Clinical and Experimental - November 18, 2020 Category: Biomedical Science Authors: Dong Ji, Mingjie Zhang, Enqiang Qin, Lunqing Zhang, Jing Xu, Yudong Wang, Gregory Cheng, Feng Wang, George Lau Tags: Correspondence Source Type: research