HELICOBACTER PYLORI INFECTION in CHILDREN with CONCURRENT CELIAC DISEASE and TYPE 1 DIABETES MELLITUS

This study aimed to evaluate the association between Hp and concomitant CD+T1DM in children. Methods: In this two-center, case-control study, children who underwent esophago-gastro-duodenoscopy were studied. CD diagnosis was established by favorable histology and serology. Hp infection was confirmed by both histology and the rapid urease test. Patients were divided into three groups as CD only (CDo), CD+T1DM, and non-CD children who underwent endoscopy as controls. Results: Among the 1431 esophago-gastro-duodenoscopies performed, 783 cases were eligible. Overall, 215 cases had CDo (mean age: 9.12 ±4.18 years, 58.1% girls), 63 cases had CD+T1DM (mean age: 9.29±4.46 years, 50.8% girls) and 505 cases were controls (mean age: 9.69±4.52 years, 56.6% girls). Hp infection rate was significantly lower in CD+T1DM group (controls: 49.7% vs CDo: 32.1% vs CD+T1DM: 20.6%, p
Source: Digestive Diseases - Category: Gastroenterology Source Type: research