Discovery of a novel inhibitor of human purine nucleoside phosphorylase by a simple hydrophilic interaction liquid chromatography (HILIC-UV) enzymatic assay.

This study provides both new tools and a new lead for developing novel Hs PNP inhibitors.
PMID: 33405358 [PubMed - as supplied by publisher]

Source: ChemMedChem - January 6, 2021 Category: Chemistry Authors: Rabuffetti M, Rinaldi F, Lo Bianco A, Speranza G, Ubiali D, de Moraes MC, Claudio Rodrigues Pereira da Silva L, Massolini G, Calleri E, Lavecchia A Tags: ChemMedChem Source Type: research