The heart of the matter: balancing potential cardiovascular risks with known benefits of gender-affirming testosterone

Over the past few years, as visibility and acceptance of gender diversity have increased, the number of people identifying as transgender or nonbinary has been rising. Based on 2015 data, transgender people comprise 0.58% of the adult U.S. population, or about 1.9 million people. A large majority of transgender people (78%) express interest in, or are currently using, gender-affirming hormones (1). However, there is little long-term safety data on the use of gender-affirming hormones, and recommendations and counseling are often extrapolated from studies in hypogonadal men, postmenopausal women, and women with polycystic ovary syndrome.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research