Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases.

Applications of iTRAQ and TMT labeling techniques to the study of neurodegenerative diseases.
Curr Protein Pept Sci. 2020 Nov 02;:
Authors: Li K, Chen Z, Yang X, Zhang Y
Abstract
Neurodegenerative diseases are caused by progressive lesions or loss of specific nerve cells, which endanger human health. However, the mechanism by which neurodegeneration manifests remains unclear. Proteomics can shed light on this question as well as help establish diagnostic standards and discover new drug targets. The power of proteomics for understanding neurodegenerative diseases has increased substantially with the application of iTRAQ and TMT labeling techniques. This review focuses on progress in these labeling techniques and their applications in neurodegeneration research.
PMID: 33143625 [PubMed - as supplied by publisher]

Source: Current Protein and Peptide Science - November 2, 2020 Category: Biochemistry Authors: Li K, Chen Z, Yang X, Zhang Y Tags: Curr Protein Pept Sci Source Type: research