Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Targeting ovarian solid tumors by Elastin-like polypeptide drug conjugates: Current trends and future prospectives
CONCLUSION: Elastin-like polypeptides (ELP), one of the thermoresponsive polymers, have been identified as drug carriers in anticancer therapy. ELP-drug conjugates have the potential and can be used effectively in combination with hyperthermia for targeting drugs to solid tumors. This review reports on the use of ELPs in cancer therapy, its biomedical applications, and recent developments to target medicines to solid ovarian tumors.PMID:34259143 | DOI:10.2174/1389203722666210713161618 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - July 14, 2021 Category: Biochemistry Authors: Deepthi Ramamurthi Moola Joghee Nanjan Chandrasekar Shanthi Bhupathi Santhosh Sunil Kumar Patnaik Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

Recent Advances in Synaptosomal Proteomics in Alzheimer's Disease
Curr Protein Pept Sci. 2021 Jun 18. doi: 10.2174/1389203722666210618110233. Online ahead of print.ABSTRACTThe current meta-analysis of the cohort review was designed to elucidate the progress made in neuroproteomics of the synaptosome. The association of the comprehensive synaptic proteome and its link to physiological or pathological settings is rapidly mounting. Chemical synapses in the brain are focal hot spots for interneuronal signaling, signal transduction, and plasticity. Structurally, synapses comprise axon termini or the presynapse (vesicles filled with neurotransmitters that function as molecular signals), synapt...
Source: Current Protein and Peptide Science - June 21, 2021 Category: Biochemistry Authors: Faraz Ahmad Shafiul Haque Vishal Chavda Ghulam Md Ashraf Source Type: research

A Mini Review on the Effectiveness of Peptoids as Therapeutic Interventions against Neurodegenerative Diseases
Curr Protein Pept Sci. 2021 Jun 15. doi: 10.2174/1389203722666210615125852. Online ahead of print.ABSTRACTNeurodegenerative diseases emerged as one of the major age-associated diseases in the recent years. Hence, the urge for understanding the mechanism and to find targeted therapeutics becomes inevitable. Peptide-based compounds emerged as one of the important tools for its therapy. But due to a lack of tolerability, specificity and proteolytic degradation, it loses its applicability in a wider sense. Thus, the search for suitable alternatives or peptidomimetics becomes an important criterion for neurotherapeutics. One of...
Source: Current Protein and Peptide Science - June 17, 2021 Category: Biochemistry Authors: Subha Sankar Paul Goutam Biswas Source Type: research

A Mini Review on the Effectiveness of Peptoids as Therapeutic Interventions against Neurodegenerative Diseases
Curr Protein Pept Sci. 2021 Jun 15. doi: 10.2174/1389203722666210615125852. Online ahead of print.ABSTRACTNeurodegenerative diseases emerged as one of the major age-associated diseases in the recent years. Hence, the urge for understanding the mechanism and to find targeted therapeutics becomes inevitable. Peptide-based compounds emerged as one of the important tools for its therapy. But due to a lack of tolerability, specificity and proteolytic degradation, it loses its applicability in a wider sense. Thus, the search for suitable alternatives or peptidomimetics becomes an important criterion for neurotherapeutics. One of...
Source: Current Protein and Peptide Science - June 17, 2021 Category: Biochemistry Authors: Subha Sankar Paul Goutam Biswas Source Type: research

A Mini Review on the Effectiveness of Peptoids as Therapeutic Interventions against Neurodegenerative Diseases
Curr Protein Pept Sci. 2021 Jun 15. doi: 10.2174/1389203722666210615125852. Online ahead of print.ABSTRACTNeurodegenerative diseases emerged as one of the major age-associated diseases in the recent years. Hence, the urge for understanding the mechanism and to find targeted therapeutics becomes inevitable. Peptide-based compounds emerged as one of the important tools for its therapy. But due to a lack of tolerability, specificity and proteolytic degradation, it loses its applicability in a wider sense. Thus, the search for suitable alternatives or peptidomimetics becomes an important criterion for neurotherapeutics. One of...
Source: Current Protein and Peptide Science - June 17, 2021 Category: Biochemistry Authors: Subha Sankar Paul Goutam Biswas Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Micro-RNA, a promising biomarker for breast and ovarian cancer: A Review
CONCLUSION: Considering all the mentioned information, it can be concluded that mi-RNAs can act as potential biomarkers for the diagnosis of breast and ovarian cancers.Recent Advances in Anti-Infective Drug Discovery.PMID:34102968 | DOI:10.2174/1389203722666210608154705 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - June 9, 2021 Category: Biochemistry Authors: Fatima Akram Noman Atique Ikram Ul Haq Zeeshan Ahmed Zuriat Jabbar Ali Nawaz Amna Aqeel Rabia Akram Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Small-molecule inhibitors targeting eIF4A in leukemia
Curr Protein Pept Sci. 2021 May 26. doi: 10.2174/1389203722666210526155808. Online ahead of print.ABSTRACTEukaryotic translation initiation factor 4A (eIF4A) is a highly conserved DEAD-box RNA helicase in eukaryotes with ATPase and RNA helicase activities. eIF4A plays an important role in cap-dependent translation at the initiation of mRNA translation, and carcinoma signal transduction pathways are focused on cap-dependent translation. eIF4A is highly expressed in a variety of cancers, and its high expression is associated with the degree of leukemia progression. Therefore, eIF4A, as a target for tumor therapy, has become ...
Source: Current Protein and Peptide Science - May 27, 2021 Category: Biochemistry Authors: Xiaofeng Jia Hong Zhou Source Type: research

Current Methods for Mass Spectrometric Analysis of Intact Proteins and Peptides
Curr Protein Pept Sci. 2021;22(2):90-91. doi: 10.2174/138920372202210308153805.NO ABSTRACTPMID:33998987 | DOI:10.2174/138920372202210308153805 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - May 17, 2021 Category: Biochemistry Authors: Timothy Veenstra Source Type: research

Current Methods for Mass Spectrometric Analysis of Intact Proteins and Peptides
Curr Protein Pept Sci. 2021;22(2):90-91. doi: 10.2174/138920372202210308153805.NO ABSTRACTPMID:33998987 | DOI:10.2174/138920372202210308153805 (Source: Current Protein and Peptide Science)
Source: Current Protein and Peptide Science - May 17, 2021 Category: Biochemistry Authors: Timothy Veenstra Source Type: research