Non-catecholamine vasopressors in the treatment of adult patients with septic shock —evidence from meta-analysis and trial sequential analysis of randomized clinical trials

ConclusionsCurrent pooled results suggest that the addition of NE to non-catecholamine vasopressors was associated with a marginally significant reduction in 28-day mortality. Moreover, they were able to shorten the length of MV, improved renal function, decreased HR, and increased the 6-h shock reversal success rate at the expense of increased the risk of hyponatremia and digital ischemia.
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research