Preliminary evaluation of serial interferon-gamma releasing assay testing in NSCLC patients treated with immune checkpoint inhibitors

Conclusions: This preliminary study revealed that 1.7% (1/59) patients had positive conversions of IGRA and that it correlated with the development of active tuberculosis. However, the clinical utility of IGRA screening remains undetermined in light of a case with a negative conversion, and further study is warranted. Nevertheless, physicians should pay attention to the potential development of tuberculosis during immunotherapy with ICIs.

Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Fujita, K., Yamamoto, Y., Kanai, O., Okamura, M., Nakatani, K., Mio, T. Tags: Tuberculosis Source Type: research