Deeper into the mediastinum: Topographical distribution and histological patterns of occult pN2 disease in NSCLC patients

Conclusions: Our results suggest that invasive mediastinal staging should be probably encouraged in NSLCL male patients, with poorly differentiated adenocarcinoma lesions of the upper lobes. Considering the current lack of well-designed randomized trials, further studies are warranted in order to validate these findings, thus eliminating occult N2 involvement that may influence treatment decision-making and survival.

Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Lioumpas, D., Tomos, P., Zaragkas, S., Fillipou, D., Tzatzadakis, N., Michos, T., Fili, N., Stamatatos, I., Balakera, C., Samiotis, I., Bouboulis, K., Kleontas, A. Tags: Lung cancer Source Type: research