Neurostimulation of Tongue Relieves Tinnitus Symptoms

Tinnitus, the sensation of ringing in the ears, is one of the most common medical conditions. Approximately 15% of the population suffers from it, but the nature of this malady makes it difficult to study and find therapeutic options. Now, a multinat...
Source: Medgadget - Category: Medical Devices Authors: Tags: ENT Neurology Source Type: blogs

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Every care provider and life sciences business says the same thing: the global pandemic emergency is acting as an unprecedented accelerant that is profoundly changing the way healthcare is delivered and R&D is conducted.    Above all, the experiences of 2020 have expanded our sense of the possibilities for technology to transform our health. We are in a new technological era. “COVID has disrupted our industry,” says Bertrand Bodson, Chief Digital Officer at Novartis. “It has highlighted our strengths and areas we now need to dial up. Healthcare’s digital moment has arrived.”&nb...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
This article outlines the evidence-based integrative treatment concept with a focus on psychosocial aspects of pain. We exemplify how the evaluation and treatment by a pain psychologist complements the dental therapy. For example, self-management techniques can assist in reducing apprehension, worries and fears, which are often associated with an increased tone of the masticatory muscles. Manifestations include clenching and grinding of teeth, orofacial pain, and other less specific symptoms such as tinnitus. The clinical relevance is illustrated by selected case studies from routine clinical practice. PMID: 32674531 [PubMed - in process]
Source: Schweizer Monatsschrift fur Zahnmedizin - Category: Dentistry Tags: Swiss Dent J Source Type: research
Abstract AIMS: Spontaneous coronary artery dissection (SCAD) is increasingly recognised as a cause of myocardial infarction, but psychological characteristics of patients with SCAD have not yet been extensively investigated. We assessed the prevalence of a broad range of psychological and clinical factors, and their inter-relationships in patients with a history of SCAD. Furthermore, we investigated whether specific clusters of patients with SCAD can be identified. METHODS: Participants were recruited between March and May 2019 from a Dutch SCAD database and completed online questionnaires...
Source: Netherlands Heart Journal - Category: Cardiology Authors: Tags: Neth Heart J Source Type: research
Abstract We provide here the first systematic review on the studies dealing with repetitive transcranial magnetic stimulation (rTMS) for traumatic brain injury (TBI) in animals and humans. Several experimental studies in animal models have explored with promising results the use of rTMS to enhance neuroprotection and recovery after TBI. However, there are surprisingly few studies that have obtained substantial evidence regarding effects of rTMS in humans with TBI, many of them are case reports investigating the heterogeneous conditions linked to TBI. The most studies have investigated the effects of rTMS in subjec...
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research
CONCLUSIONS: Due to paucity of the evidence and the very low certainty of that which is available the effectiveness and safety profile of antiseptics in the treatment of CSOM is uncertain. PMID: 31902140 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
ConclusionThe patient started treatment using B12 vitamin, thiamine, and physical therapy. Currently, despite reported balance improvement, he needs ambulation support. He features nystagmus, bilateral dysmetria, mild dysdiadochokinesia, continuous tinnitus in his left ear, blurred vision, and neck pain while moving it.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
This report describes the use of acupuncture in the treatment of a 71-years-old female with chronic neck pain who suffered from a left-sided tinnitus for 2 years, as well. The tinnitus and neck pain severity was rated as 7 and 6 respectively on a numeric rating scale (NRS) of 10. On examination, she had restricted cervical range of motion and several myofascial trigger points in cervical muscles. Audiometric tests of patient were normal. She received trigger point acupuncture of cervical muscles twice per week for 10 sessions. Her tinnitus completely disappeared after third session and did not return during 5 years follow-...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
CONCLUSION: Dysregulated psychophysiologic interactions may affect the development of tinnitus in patients with chronic TMD. PMID: 31247060 [PubMed - as supplied by publisher]
Source: Journal of Orofacial Pain - Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
CONCLUSION: Our results suggest that rTMS is a beneficial therapeutic treatment for chronic tinnitus patients and the dual-site treatment was the most effective in terms of both tinnitus complaint and quantitative indices. Thus, subjective reports and electrophysiological signatures may be complementary for the diagnosis/prognosis of tinnitus. PMID: 31092043 [PubMed - in process]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
Conclusion The first crystal structure of a human nAChR domain with an α-Ctx is presented. The structure revealed the interactions between α-Ctx RgIA and the (+) side of neuronal nAChR α9-ECD in high detail. Based on the structure of this complex, models of human α9α10 nAChR ECD with fully formed binding sites were constructed with RgIA bound to each of them. Our MD simulations suggest that the favorable binding site of RgIA in the human α9α10 nAChR ECD consists of either α9 or α10 subunits as the (+) side and of an adjacent α9 rather than α10 subunit as th...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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