Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease

Conclusions: Our findings reinforce the positive therapeutic effects on AD models with both Aβ and tau pathology induced by FUS/MB-mediated BBB opening, further supporting the potential of this treatment regime for clinical applications.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Yuanyuan Shen, Lingchen Hua, Chih-Kuang Yeh, Liming Shen, Ming Ying, Zaijun Zhang, Gongping Liu, Shupeng Li, Siping Chen, Xin Chen, Xifei Yang Tags: Research Paper Source Type: research