Retrospective Comparison of Contrast-Enhanced Spectral Mammography with Digital Mammography in Assessing Tumor Size in 668 Cases of Breast Cancer.

CONCLUSIONS CESM is a new diagnostic method in breast cancer. The accuracy of measurement of tumor size using CESM is independent of lesion size, but it overestimates the size by 5 mm on average. The difference is not dependent on grading, biological subtype of the carcinoma, or patient age. They concern the histopathological type, and values are significantly greater in pre‑invasive carcinomas. PMID: 32994388 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research

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ConclusionsThis study contains the largest population dataset of ILC evaluated to date. While total breast cancer incidence rates in Ontario are largely unchanged, ILC incidence rates are steadily increasing and there is a trend towards diagnosis of ILC at a later stage. These trends highlight the ongoing diagnostic and treatment challenge ILC presents for patients and clinicians.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Background: Ductal carcinoma in situ (DCIS) identified by screening mammography accounts for 20% of breast cancer diagnoses, and microinvasion (DCIS-M) is found in 5% –10%. There are no defined treatment guidelines for palpable DCIS or DCIS-M. The role of screening mammography is now being questioned across the world and in the developing world with no national screening programs, women with DCIS present with a palpable lump in the breast. We conducted a retros pective audit of women with DCIS treated at our institution to classify palpable DCIS and DCIS-M as distinct clinical stages and emphasize the need for a chan...
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Optimal Diagnosis Source Type: research
Introduction: Lobular breast cancer is less common that ductal carcinoma, and can be more difficult to diagnose by both physical examination and mammography. Previous studies have shown a general increase in lobular breast cancer rates over the 1980s-1990s, however this was during a time when the use of combined hormone replacement therapy (CHRT) – a known risk factor for breast cancer – was increased. As CHRT use has declined since the mid 2000s, this study endeavoured to evaluate current trends in the incidence of invasive lobular carcinoma (ILC) in women diagnosed with breast cancer, and to describe the 5-, ...
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Local Regional Treatment – Surgery Source Type: research
Background: Low-risk ductal carcinoma in situ (DCIS) lesions carry a risk of progressing to invasive breast cancer (iBC). Therefore, women with DCIS undergo surgery ±radiotherapy which will yield many of them no/limited survival benefit whilst the associated side-effects can significantly impact their quality of life (QoL). The safety of active surveillance (AS) via yearly mammographic screening for low-risk DCIS is now being investigated. AS minimizes the phy sical burden associated with the standard treatments, but foregoing treatment could cause increased worry about progression of the DCIS lesion to iBC.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Local Regional Treatment – Surgery Source Type: research
This study aimed to determ...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
o Dong-Xu Liu Breast cancer is the most common cancer in women worldwide. Accurate early diagnosis of breast cancer is critical in the management of the disease. Although mammogram screening has been widely used for breast cancer screening, high false-positive and false-negative rates and radiation from mammography have always been a concern. Over the last 20 years, the emergence of “omics” strategies has resulted in significant advances in the search for non-invasive biomarkers for breast cancer diagnosis at an early stage. Circulating carcinoma antigens, circulating tumor cells, circulating cell...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Authors: Gilmore R, Prasath V, Habibi M Abstract Paget's disease of the breast (PDB) is a rare breast carcinoma believed to arise from an underlying in situ or invasive ductal cancer that migrates through the epidermis causing characteristic skin changes including scaling, redness, and itching of the nipple, areola, and sometimes the surrounding skin. Although Paget's may mimic benign conditions such as contact or allergic eczema and mastitis, it should remain a strong consideration in the differential diagnosis , especially in peripartum women for whom benign conditions such as bacterial mastitis from breastfeedin...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Rationale: Triple or more primary malignancies are rare, with only 23 previous cases including breast cancer reported in the English language studies between January 1990 and December 2019. Patient concerns: The patient was a 67-year-old woman with a mass in her right breast. She had a previous history of uterine and colon cancer. Both ultrasonography and mammography revealed a Breast Imaging Reporting and Data System (BI-RADS) category 3 breast lesion, in which proliferative nodules are more likely. Given her previous history of 2 malignancies, her doctors strongly recommended a biopsy. Diagnosis and interventions: ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
CONCLUSION: In our cohort, expectant management of FEA alone appears to be a safe option as our upstaging rate to DCIS or invasive cancer for FEA diagnosed on core biopsy was only 4%. Our study suggests that close follow-up is a safe and feasible option for pure FEA without a radiographic discordance found on core biopsy. PMID: 32816560 [PubMed - as supplied by publisher]
Source: The American Surgeon - Category: Surgery Authors: Tags: Am Surg Source Type: research
CONCLUSION: The female predominance of diseases of the thyroid and breast makes difficult the separation of an expected association with a casual linkageThe relationship between the co-occurrence of breast and thyroid cancer remains controversial and inconclusive. KEY WORDS: Breast cancer, Breast surgery, Hormone therapy, Thyroid cancer, Thyroidectomy. PMID: 32719185 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
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