Blocking enzyme's self-destruction process may mitigate age-related diseases

(University of Pennsylvania School of Medicine) Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology. For the first time, researchers in the Perelman School of Medicine at the University of Pennsylvania show how the self-eating cellular process known as autophagy is causing the SIRT1 enzyme, long known to play a role in longevity, to degrade over time in cells and tissue in mice.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news