Gut Microbiota-Metabolome Changes in Children With Diarrhea by Diarrheagenic E. coli

Conclusion: Stool samples from healthy children and children positive for DEC displayed a differential metabolome and microbiota composition. A strong correlation between a gut microbiota species and certain metabolites, such as histamine and L-ornithine, was found in the DEC group. This information might be useful to identify mechanisms and signaling molecules involved in the crosstalk between microbiota and DEC pathotypes.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research