Calcium signaling consequences of RyR2 mutations associated with CPVT1 introduced via CRISPR/Cas9 gene editing in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs): Comparison of RyR2-R420Q, F2483I and Q4201R
hiPSC-CMs created from catecholaminergic polymorphic ventricular tachycardia (CPVT1) patients have been used to study the pathology of CPVT1.
Source: Heart Rhythm - Category: Cardiology Authors: Xiao-hua Zhang, Hua Wei, Yanli Xia, Martin Morad Source Type: research
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