An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility.

Conclusions: The results suggest an important role of DNA methylation in the normal homeostasis of cardiomyocytes and during cardiac stress, which could make it an interesting target for cardiac therapy. PMID: 32885664 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32885664?dopt=Abstract

Source: Circulation - September 3, 2020 Category: Cardiology Authors: Madsen A, Höppner G, Krause J, Hirt MN, Laufer SD, Schweizer M, Tan WLW, Mosqueira D, Anene-Nzelu CG, Lim I, Foo RSY, Eschenhagen T, Stenzig J Tags: Circulation Source Type: research