Loss of bone density and bone strength following premenopausal risk –reducing bilateral salpingo-oophorectomy: a prospective controlled study (WHAM Study)

ConclusionThis prospective, controlled study of bone health following RRBSO or premenopausal oophorectomy demonstrated substantial loss of bone density and bone strength following RRBSO. HT prevented loss of bone density and bone stiffness, although there was still a modest decrease in lumbar spine aBMD in HT users. These findings may inform decision-making about RRBSO and clinical management following premenopausal oophorectomy.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research