Efficacy and tolerability of high versus low dose lenalidomide maintenance therapy of multiple myeloma after autologous blood stem cell transplantation.

CONCLUSIONS: LenMT dose correlated with efficacy and toxicity. High rates of dose reductions during CT argue against a high starting dose. However, continuous up- and down-titration for each patient to the current maximum tolerated dose is prudent.
PMID: 32817078 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - August 16, 2020 Category: Cancer & Oncology Authors: Fenk R, Giagounidis A, Goldschmidt H, Heinsch M, Rummel M, Kröger N, Boquoi A, Lopez D, Gerrlich C, Baier J, Liesenjohann S, Hauck K, Savickaite I, Mai EK, Aul C, Strapatsas J, Dienst A, Kondakci M, Haas R, Kobbe G Tags: Clin Cancer Res Source Type: research