Increased carcinoembryonic antigen expression on the surface of lung cancer cells using gold nanoparticles during radiotherapy
The carcinoembryonic antigen (CEA), also known as CD66, is an onco-fetal antigen expressed on some tissues during fetal development. After birth, CEA levels drop to very low concentrations but circulates in high concentrations in adult patients with certain malignancies [1]. In its first description in 1965, CEA was assumed to be a tumor-specific antigen for colon cancer [2]. Today it is known for being a tumor-associated antigen in a variety of other cancers including lung [3], breast [3], colorectal [4], and cervical [5]; which are predominantly epithelial tumors.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Romy Mueller, Sayeda Yasmin-Karim, Kaylie DeCosmo, Ana Vazquez-Pagan, Srinivas Sridhar, David Kozono, Juergen Hesser, Wilfred Ngwa Tags: Original paper Source Type: research
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