Increased carcinoembryonic antigen expression on the surface of lung cancer cells using gold nanoparticles during radiotherapy

The carcinoembryonic antigen (CEA), also known as CD66, is an onco-fetal antigen expressed on some tissues during fetal development. After birth, CEA levels drop to very low concentrations but circulates in high concentrations in adult patients with certain malignancies [1]. In its first description in 1965, CEA was assumed to be a tumor-specific antigen for colon cancer [2]. Today it is known for being a tumor-associated antigen in a variety of other cancers including lung [3], breast [3], colorectal [4], and cervical [5]; which are predominantly epithelial tumors.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research