Renalase is a novel target gene of hypoxia-inducible factor-1 in protection against cardiac ischaemia-reperfusion injury

Conclusion
These findings have revealed renalase as a novel target gene of HIF-1α in protection against myocardial I/R injury, which provided a basis for therapeutic strategies for enhancing cardiomyocyte survival in patients associated with ischaemic heart diseases.

Source: Cardiovascular Research - January 16, 2015 Category: Cardiology Authors: Du, M., Huang, K., Huang, D., Yang, L., Gao, L., Wang, X., Huang, D., Li, X., Wang, C., Zhang, F., Wang, Y., Cheng, M., Tong, Q., Qin, G., Huang, K., Wang, L. Tags: Cardiac biology and remodelling Source Type: research