Epigenetic repression of AT2 receptor is involved in β cell dysfunction and glucose intolerance of adult female offspring rats exposed to dexamethasone prenatally.

In conclusion, continuous epigenetic repression of AT2R before and after birth may be involved in β cell dysfunction and glucose intolerance of the PDE adult female offspring. PMID: 32791177 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32791177?dopt=Abstract

Source: Toxicology and Applied Pharmacology - August 9, 2020 Category: Toxicology Authors: Kou H, Gui S, Dai Y, Guo Y, Wang H Tags: Toxicol Appl Pharmacol Source Type: research