Mood disorders and cognitive impairment in the course of increasing disability in patients suffering from amyotrophic lateral sclerosis.
CONCLUSIONS: (1) The gradually developing motor neuron loss of the anterior horns of the spinal cord is reflected in physical fitness impairment in the ALS patients. (2) The exacerbation of cognitive impairment accompanies the intensifying physical disability. (3) The exacerbation of depression in the course of amyotrophic lateral sclerosis is of transient nature. PMID: 32772061 [PubMed - in process]
Publication date: October 2020Source: Brain, Behavior, and Immunity, Volume 89Author(s): Mario Gennaro Mazza, Rebecca De Lorenzo, Caterina Conte, Sara Poletti, Benedetta Vai, Irene Bollettini, Elisa Maria Teresa Melloni, Roberto Furlan, Fabio Ciceri, Patrizia Rovere-Querini, COVID-19 BioB Outpatient Clinic Study group, Francesco Benedetti
Publication date: October 2020Source: Brain, Behavior, and Immunity, Volume 89Author(s): Xiaoqin Liu, Trine Munk-Olsen, Clara Albiñana, Bjarni J. Vilhjálmsson, Emil M. Pedersen, Vivi Schlünssen, Marie Bækvad-Hansen, Jonas Bybjerg-Grauholm, Merete Nordentoft, Anders D. Børglum, Thomas Werge, David M. Hougaard, Preben B. Mortensen, Esben Agerbo
Publication date: October 2020Source: Brain, Behavior, and Immunity, Volume 89Author(s): Fernando Lopes, Fernando A. Vicentini, Nina L. Cluny, Alexander J. Mathews, Benjamin H. Lee, Wagdi A. Almishri, Lateece Griffin, William Gonçalves, Vanessa Pinho, Derek M. McKay, Simon A. Hirota, Mark G. Swain, Quentin J. Pittman, Keith A. Sharkey
Authors: Han HJ, Park HJ, Yun U, Choi YC PMID: 33029983 [PubMed]
CONCLUSIONS: Individually customized, multicomponent exercise programs lead to improved levels of cognitive function, depression, and quality of life, especially among those who are more frail. PMID: 33029968 [PubMed]
CONCLUSIONS: Subcortical gray-matter structures are involved in the neurodegenerative process of ALS before cognitive impairment becomes evident. PMID: 33029965 [PubMed]
I woke up Wednesday morning to the news that Stephen Hawking had passed away. My first thought made me smile — that this incredible scientist who seemed to just will himself to stay alive against overwhelming odds, died on March 14th — Pi Day. Maybe that was his choice. Who knows? Stephen Hawking was a thinker — a brilliant scientist, professor and author who was known for his groundbreaking work in physics and cosmology. His books aimed to make science accessible to everyone. His more well-known works include A Brief History of Time, The Universe in a Nutshell, and A Briefer History of Time. At th...
(LONDON) — Stephen Hawking, whose brilliant mind ranged across time and space though his body was paralyzed by disease, died early Wednesday, a University of Cambridge spokesman said. He was 76 years old. Hawking died peacefully at his home in Cambridge, England. The best-known theoretical physicist of his time, Hawking wrote so lucidly of the mysteries of space, time and black holes that his book, “A Brief History of Time,” became an international best seller, making him one of science’s biggest celebrities since Albert Einstein. “He was a great scientist and an extraordinary man whose work a...
Amyotrophic lateral sclerosis is a terminal motor neuron disease, with progressive paralysis, dysarthria, dysphagia and respiratory disabilities. Eye Tracking based computer systems (ETCS) facilitate communication and participation in advanced quadriplegic and anarthric disease state. The impact of ALS on patients and caregivers wellbeing is controversial, with patients showing surprisingly preserved psychological functioning in some studies. Quality of Life, depression and the impact of communicative functioning, especially ETCS usage in the advanced, quadriplegic disease state has not yet been investigated in a direct, f...