Acute isotonic hyponatremia after single dose histidine-tryptophan-ketoglutarate cardioplegia: an observational study.

CONCLUSION: Administration of histidine-tryptophan-ketoglutarate cardioplegia during cardiac surgery leads to acute moderate to severe isotonic hyponatremia, which resolves spontaneously in the first 18 hours perioperatively. Correction with hypertonic saline is not necessary.
PMID: 32755277 [PubMed - as supplied by publisher]

Source: Perfusion - August 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: van Houte J, Bindels AJ, Houterman S, Dong PV, den Ouden M, de Bock NE, Verberkmoes NJ, Curvers J, Bouwman AR Tags: Perfusion Source Type: research