The effect of simulation strategies on prediction of power deposition in the tissue around electronic implants during magnetic resonance imaging.

This study examines the effect of variations in anatomical details of the human body model and implant's geometry on predicted SAR values during MRI in a patient with a DBS implant. We used patient-derived models of a DBS implant as it covers a large cross section of the body from head to upper chest and performed numerical simulations to calculate the maximum SAR during MRI at 1.5T (64 MHz) and 3T (127 MHz). We then assessed the effect of uncertainties in dielectric properties of tissue, complexity of body model, truncation of body/DBS model, and DBS lead's geometry on SAR. Our results showed that 40% variation in the conductivity of individual tissues in a heterogeneous body model caused a peak of 7% variation in maximum SAR value at 64 MHz, and 11% variation in SAR at 127 MHz. SAR predictions from a homogeneous body model with a conductivity range of 0.01S/m → 1S/m could cover the full range of SAR variations predicted by the heterogeneous body model. Truncation of body model below the implanted pulse generator changed the predicted SAR by 7% at 1.5T and 20% at 3T while saving 250% and 148% in computational time and memory allocation, respectively. In contrast, variation in DBS lead geometry significantly changed the SAR by up to 51% at 64 MHz and 69% at 127 MHz. These results suggest that the error introduced by simplifying the implant's geometry could negate the benefit of using a realistic body model, should such model be used at the expense of oversimplifying implant...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research