Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium

Conclusions The inference from the present study is that CPB burst-suppression mediates the effects of physical function, lowest CPB temperature, and electroencephalogram alpha power on delirium.Editor ’s PerspectiveWhat We Already Know about This TopicAssociations between intraoperative burst-suppression and postoperative delirium have been reported.The causal significance of these associations is unknown.What This Article Tells Us That Is NewIn a retrospective observational substudy of 159 patients undergoing cardiac surgery, there is evidence that burst-suppression during cardiopulmonary bypass mediates the effect of physical function, temperature during cardiopulmonary bypass, and intraoperative electroencephalographic alpha power on postoperative delirium. Delirium was also associated with decreased broadband power in the intraoperative electroencephalogram.
Source: Anesthesiology - Category: Anesthesiology Source Type: research