Correlation of Serum Adipolin with Epicardial Fat Thickness and Severity of Coronary Artery Diseases in Acute Myocardial Infarction and Stable Angina Pectoris Patients

Objective: Adipolin/C1q/TNF-related protein-12 is a family of CTRPs that is highly expressed in adipose tissue and has glucose-lowering and anti-inflammatory effects. Various risk factors have been suggested in the incidence of cardiovascular diseases such as a decrease in anti-inflammatory or an increase in inflammatory factors. The purpose of the present study was to investigate the correlation of adipolin with anthropometric, angiographic, echocardiographic, and biochemical parameters. Subject and Methods: A total of 90 patients who were candidates for angiography were included in the study and divided into three groups: 30 patients with acute myocardial infarction (AMI), 30 patients with stable angina pectoris (SAP), and 30 subjects as control group with a history of chest pain but normal angiography. Anthropometric, angiographic, echocardiographic, and biochemical parameters were measured in all subjects. Results: Serum adipolin levels were significantly decreased in patients with AMI compared with SAP and control groups (P
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research