Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3 β / β -catenin pathway

Conclusion: Our findings revealed a previously unrecognized function of MSR1 in macrophages during fracture repair. Targeting MSR1 might, therefore, be a new therapeutic strategy for fracture repair.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Shu-Jie Zhao, Fan-Qi Kong, Jian Jie, Qing Li, Hao Liu, An-Di Xu, Ya-Qing Yang, Bin Jiang, Dong-Dong Wang, Zhong-Qiu Zhou, Peng-Yu Tang, Jian Chen, Qian Wang, Zheng Zhou, Qi Chen, Guo-Yong Yin, Han-Wen Zhang, Jin Fan Tags: Research Paper Source Type: research