Quantitative chemical imaging of breast calcifications in association with neoplastic processes
Conclusion: SRS, combined with SHG, can be a valuable tool in better understanding calcifications in carcinogenesis, diagnosis, and possible prognosis. This study not only reveals previously unknown large variations of breast microcalcifications in association with local malignancy but also corroborates the clinical value of linking microcalcification chemistry to breast malignancy. More importantly, it represents an important step in the development of a label-free imaging strategy for breast cancer diagnosis with tremendous potential to address major challenges in diagnostic discordance in pathology.
Source: Theranostics - Category: Molecular Biology Authors: Kseniya S. Shin, Mint Laohajaratsang, Shuaiqian Men, Benjamin Figueroa, Suzanne M. Dintzis, Dan Fu Tags: Research Paper Source Type: research
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