Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma

Conclusion:The promoting function of Rab22a-NeoF1 is dependent on its K7 acetylation in osteosarcoma, and targeting this acetylation (e.g., C646) may benefit cancer patients, in particular osteosarcoma patients, who are positive for the Rab22a1-38.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Xiaoting Liang, Xin Wang, Yaohui He, Yuanzhong Wu, Li Zhong, Wen Liu, Dan Liao, Tiebang Kang Tags: Research Paper Source Type: research