JP1 suppresses proliferation and metastasis of melanoma through MEK1/2 mediated NEDD4L-SP1-Integrin α v β 3 signaling

Conclusions: JP1 was developed as a novel peptide that indicated therapeutic roles on proliferation and metastasis of melanoma through the NEDD4L-SP1-Integrin αvβ3 signaling.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Jiahua Cui, Chuanjun Shu, Jin Xu, Dongyin Chen, Jin Li, Kun Ding, Minjuan Chen, Aiping Li, Jingdong He, Yongqian Shu, Liuqing Yang, Ruiwen Zhang, Jianwei Zhou Tags: Research Paper Source Type: research