Maternal and neonatal outcomes and prognostic factors in acute fatty liver of pregnancy

The prevalence of liver diseases in pregnancy is estimated at near 3% of all pregnancies in developed countries[1], including liver diseases induced by pregnancy or those revealed during pregnancy. Five liver disorders are specific to pregnancy: hyperemesis gravidarum, intrahepatic cholestasis, liver disorders associated with pre-eclampsia (PE), Hemolysis, Elevated Liver enzymes, and Low Platelet count syndrome (HELLP), and Acute Fatty Liver of pregnancy (AFLP). AFLP, initially described in 1940 [2], typically occurs during the third trimester of pregnancy, with an incidence ranging between 1/5,000 and 1/20,000 pregnancies [3 –6].

Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - June 25, 2020 Category: OBGYN Authors: Y. Joueidi, K. Peoc ’h, M. Le Lous, G. Bouzille, C. Rousseau, E. Bardou-Jacquet, C. Bendavid, L. Damaj, B. Fromenty, V. Lavoué, C. Moreau Tags: Full length article Source Type: research