The β2‐glycoprotein I/HLA‐DR complex is the major autoantibody target in obstetric antiphospholipid syndrome

ConclusionsThe anti ‐β2GPI/HLA‐DR antibody is frequently associated with RPL. Detection of these autoantibodies is useful in understanding the pathogenesis of RPL. Our findings will potentially provide new therapeutic modalities for patients with obstetric APS.

Source: Arthritis and Rheumatology - June 23, 2020 Category: Rheumatology Authors: Kenji Tanimura, Shigeru Saito, Mikiya Nakatsuka, Takeshi Nagamatsu, Tomoyuki Fujii, Atsushi Fukui, Masashi Deguchi, Yuki Sasagawa, Noriko Arase, Hisashi Arase, Hideto Yamada Tags: FULL LENGTH Source Type: research