Effective Pharmacophore for CDC25 Phosphatases Enzyme Inhibitors: Newly Synthesized Bromothiazolopyrimidine Derivatives.

CONCLUSION: The novel bromothiazolopyrimidine derivatives showed promising in vitro anticancer activities against colon cancer HCT116 and lung cancer A549 cell lines comparable to the anticancer drug doxorubicin. PMID: 32560601 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32560601?dopt=Abstract

Source: Mini Reviews in Medicinal Chemistry - June 18, 2020 Category: Chemistry Authors: El-Shahat M, Salama MAM, El-Farargy AF, Ali MM, Ahmed DM Tags: Mini Rev Med Chem Source Type: research