A single dose of doxycycline after an Ixodes ricinus tick bite to prevent Lyme borreliosis: an open-label randomized controlled trial

Lyme borreliosis is the most prevalent tick-borne disease in the northern hemisphere.1 Over the last decades, marked increases in the incidence of Lyme borreliosis have been reported in several Western European countries and the United States (US), with substantial impact on public health.2 –6 Erythema migrans is the most common early skin manifestation of the disease, and responds well to antibiotic treatment.7 However, erythema migrans is often not observed preceding disseminated Lyme borreliosis manifestations such as neuroborreliosis, Lyme arthritis and Lyme carditis.

Source: Journal of Infection - June 17, 2020 Category: Infectious Diseases Authors: M.G. Harms, A. Hofhuis, H. Sprong, S.C. Bennema, J.A. Ferreira, M. Fonville, A. Docters van Leeuwen, W.J.J. Assendelft, H.C.P.M. Van Weert, W. Van Pelt, C.C. Van den Wijngaard Source Type: research