Resection margin histology may predict intermediate-term outcomes in children with rectosigmoid Hirschsprung disease

Conclusion1 –2 year follow-up may be insufficient to determine if resection margin histology correlates with outcomes. Patient-reported quality of life surveys, although limited in number, suggest that neurotransmitter imbalance at the resection margin may predict poor outcomes in HSCR patients. This study s upports the concept that the ganglionated portion of the remaining colon post-surgery may not sustain normal bowel function.
Source: Pediatric Surgery International - Category: Surgery Source Type: research