MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF- κB activation.

This study found that MALT1, a key signal transduction cascade, can mediate EGFR-induced NF-kB activation in GBM and may be potentially used as a novel therapeutic target for GBM.
PMID: 32452133 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - May 24, 2020 Category: Molecular Biology Authors: Liu X, Yue C, Shi L, Liu G, Cao Q, Shan Q, Wang Y, Chen X, Li H, Wang J, Gao S, Niu M, Yu R Tags: J Cell Mol Med Source Type: research