A Novel PET Probe for Brown Adipose Tissue Imaging in Rodents

ConclusionsUnlike [18F]FDG, [18F]BODIPY 1 showed prominent accumulation in BAT under both inactive and stimulated status. [18F]BODIPY 1 may serve as a valuable BAT PET agent to possibly assess BAT mitochondria density, thus BAT thermogenic capacity after further evaluation.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research

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In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
A 53-year-old male with history of colon cancer status post neoadjuvant chemotherapy, radiation and colectomy, hyperlipidemia, non-insulin-dependent diabetes mellitus, obesity, hernia repair, and asthma presented to the urology clinic complaining of left inguinal swelling. Upon presentation, vital signs were unremarkable, but physical exam revealed a firm, palpable, nontender abnormality of the left inguinal region. Subsequent CT scan with IV contrast revealed a large presacral fluid collection (7.0  × 2.4 cm) and complex cystic structure arising from the left tunica albuginea (3.8 × 3.0 cm) adjacent to...
Source: Urology - Category: Urology & Nephrology Authors: Tags: Grand Rounds Source Type: research
I’ve been wearing my Fitbit for a couple of years and only remove it when I shower. I use it to track my sleep and its smart alarm wakes me up at the optimal time every morning. With the pocketable Kardia, I regularly check my ECG at home to detect any anomalies. For an in-depth analysis of what my genetic makeup predisposes me to, I had my whole genome sequenced. And I bring relevant data to my general practitioner during my checkups so that we can decide on preventive measures. In short, I’m trying to live like the patient of the future. However, posing as such a patient is not feasible for many among us. ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Lifestyle medicine E-Patients Health Sensors & Trackers Healthcare Design Medical Education Personalized Medicine sleep stress food scanner sleep apnea Apple Watch Dr. Vernes Baylor ACLM Source Type: blogs
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
A 59-year-old woman with history of breast cancer and tuberculosis was referred to our hospital complaining of abdominal pain, distention and feeling feverish. A triphasic CT scan showed several cystic liver lesions, with a 110x72mm septate lesion in segments II-III with infiltrative morphology, as well as mediastinal and paraaortic lymph nodes(Image 1). A malignant etiology could not be ruled out.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
CONCLUSION: prompt diagnosis and more aggressive thromboprophylaxis in patients with inherited or acquired risk factors may prevent the negative evolution towards bowel necrosis of SMVT. KEY WORDS: Colorectal surgery, Superior mesenteric vein thrombosis, Hypercoagulable disorders, Thromboprophylaxis. PMID: 32390649 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Abstract Body size is emerging as a novel and clinically-relevant patient factor in bladder cancer research. Historically, a patient's body mass index (BMI) has been used as a proxy for obesity but it shows inconsistent associations with risk of developing the disease as well as with most clinical outcomes. More specific body composition features can be derived for patients using a variety of methods. To date, skeletal muscle measurements derived from preoperative computed tomography scans have shown the most consistent associations with clinical outcomes. Importantly, skeletal muscle can potentially be modified t...
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
Conclusions: Serum triglycerides have potential as a predictive indicator for AL, which may improve the treatment and outcomes of patients with AL. PMID: 32285713 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
CONCLUSIONS: Our findings support the protective effect a normal weight against advanced adenomas. Reduction of BMI value should be pursued in healthy programs. PMID: 32233893 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
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