Bacterial biofilms in infective endocarditis: an in vitro model to investigate emerging technologies of antimicrobial cardiovascular device coatings

ConclusionThese results demonstrate the establishment of a novel in vitro model for bacterial biofilm growth on porcine aortic roots mimicking IE. The model will allow to identify predilection sites of valves for bacterial adhesion and biofilm growth and it may serve as baseline for further research on IE therapy and prevention, e.g. the development of antimicrobial transcatheter approaches to IE.Graphic abstract

http://link.springer.com/10.1007/s00392-020-01669-y

Source: Clinical Research in Cardiology - May 21, 2020 Category: Cardiology Source Type: research