[Voriconazole-induced lentigines on photo-exposed skin: A little-known complication].
We present a new case in which the original feature is the very short time of onset.
PATIENTS AND METHODS: A 9-year-old immunosuppressed girl treated with voriconazole for 3 months presented lentigines in exposed areas after only 4 weeks of exposure.
DISCUSSION: The literature contains only around ten cases of photo-distributed lentigines under voriconazole in children. The condition can appear very early, as in our case. Voriconazole also appears to induce cutaneous squamous cell carcinomas and even melanoma. The benefit-risk ratio of prescribing this drug must therefore be carefully evaluated, and close clinical monitoring and photoprotection must be instituted.
PMID: 32414507 [PubMed - as supplied by publisher]
Source: Annales de Dermatologie et de Cenereologie - Category: Dermatology Authors: Marcaillou M, Brun A, Mazereeuw-Hautier J Tags: Ann Dermatol Venereol Source Type: research
More News: Cancer & Oncology | Carcinoma | Children | Dermatology | Genetics | Girls | Melanoma | Skin | Skin Cancer | Squamous Cell Carcinoma