Antiplatelet activity of astaxanthin in control- and high cholesterol-fed rats mediated by down-regulation of P2Y12, inhibition of NF- κB, and increasing intracellular levels of cAMP.

In conclusion, antiplatelet effects of ASTX involve ROS scavenging, inhibiting NF-κB activity, down-regulating P2Y12 expression, and increasing intracellular levels of cAMP that are attributed to its antioxidant, hypolipidemic, and anti-inflammatory effects. PMID: 32379559 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32379559?dopt=Abstract

Source: Platelets - May 9, 2020 Category: Hematology Tags: Platelets Source Type: research