A prospective study of estimated glomerular filtration rate and outcomes in patients with atrial fibrillation: The Loire Valley Atrial Fibrillation Project.

CONCLUSION Incidence rates of IS/TE, mortality and bleeding increased with reducing eGFR, across the whole range of renal function. OAC use was associated with a lower incidence of IS/TE and mortality at 1 year, compared with non-anticoagulated individuals in all categories of renal function as measured by eGFR. The NCB balancing IS against serious bleeding was positive, in favour of OAC use amongst patients with renal impairment. PMID: 24356875 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24356875?dopt=Abstract

Source: Chest - December 19, 2013 Category: Respiratory Medicine Authors: Banerjee A, Fauchier L, Vourc'h P, Andres CR, Taillandier S, Halimi JM, Lip GY Tags: Chest Source Type: research