Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-FGF23-Klotho axis.

This study confirmed that astragalus could inhibit the aging of BMSCs and improve the osteogenesis ability by regulating the VD-FGF23-Klotho pathway. This study provided a certain research basis for the therapeutic of traditional Chinese medicine (TCM) on primary osteoporosis.
PMID: 32355520 [PubMed]

Source: International Journal of Clinical and Experimental Pathology - May 3, 2020 Category: Pathology Authors: Pu X, Chai Y, Guan L, Li W, Gao J, Jiang Z, Li Q, Wu Y, Chen Y Tags: Int J Clin Exp Pathol Source Type: research