Big Pharma’s Phony Heart Drug Failure
Get this: Big Pharma giant Merck has been trying to re-package one of Nature’s most potent heart health allies and sell it to you as a heart “drug.” They heavily lobbied the FDA to get it approved in the U.S. But a few weeks ago they had to pull it from the approval process.1 Why? [...]Related Posts:Holiday Fat-Fighting SecretYour Brain On Carnosine
Treatment with cholesterol-lowering statin drugs does not boost recovery in people with severe COVID-19 and may increase their risk for death from the virus, a study published Tuesday by PLOS ONE found.
Observational studies suggested patients with COVID-19 taking statins have better outcomes. A new review looks at trials underway assessing lipid-modifying agents to treat or prevent COVID-19.Medscape Medical News
STATINS are a group of medicines that can help lower the level of low-density lipoprotein cholesterol in the blood. Like many medicines, there are possible side effects.
Conclusion: There were no clear consistent relationships between cholesterol and cognitive decline or dementia in this older adult group, nor was there evidence of effect modification by statin use. Further work is needed in younger populations to understand the role of cholesterol across the life-course and to identify any relevant intervention points. This is especially important if modification of cholesterol is to be further evaluated for its potential influence on risk of cognitive decline or dementia.Dement Geriatr Cogn Disord
British Journal of Cancer, Published online: 26 October 2021; doi:10.1038/s41416-021-01604-6Statin use is associated with a reduced incidence of colorectal cancer expressing SMAD4
AbstractPurpose of ReviewFamilial hypercholesterolemia (FH) is a monogenic disorder characterized by high plasma levels of low-density lipoprotein cholesterol (LDL-C) since birth and a high risk of premature cardiovascular disease. The genetic defect is carried in only one allele in heterozygous FH (HeFH) or in both in the most severe homozygous FH (HoFH). Current guidelines recommend to reduce substantially LDL-C levels in these high-risk patients, with the need to use association therapy combining agents with different mechanisms of action. As most cases of FH are attributable to mutations in the gene encoding the low-de...
The labeling of statins has been revised to remove the contraindication for use during pregnancy.For a select few women at high risk for cardiovascular events, statins may provide more benefit than risk, even during pregnancy. Most women do not have this high risk, however, and should still avoid statins during pregnancy.
STATINS are a group of medicines that can help lower the level of low-density lipoprotein cholesterol in the blood. They can lower your risk of heart attack and stroke. However, they can cause side effects, two of which can be spotted on your nose.
The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arteri...
Eur J Pharm Sci. 2021 Oct 21:106005. doi: 10.1016/j.ejps.2021.106005. Online ahead of print.ABSTRACTRosuvastatin (ROS) is an anti-cholesterol drug belonging to statin drugs. A multi-spectroscopic approach combined with a molecular modeling technique was used to assess ROS association with human serum albumin (HSA). Besides, an HSA immobilized surface plasmon resonance (SPR) chip was used to obtain kinetic parameters (ka, kd, and KD). Fluorescence quenching titrations revealed that ROS interacts with HSA via a dynamic, exothermic, enthalpy-driven mechanism. Hydrogen bonds and van der Waals interactions as the most prevalent...